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Vacuum paddle dryer

Vacuum Paddle Dryer

Pharmadry® - series PH 50 - PH 4000

The Pharmadry® vacuum paddle dryer with short drying times is well suited for the drying of freely flowing, sensitive pharmaceutical ingredients and fine chemicals. Designed to meet stringent cGMP and FDA guidelines

Agitator supported at the rear, with externally exchangeable mechanical seal. Designed for frequent product changes. Excellent cleanability using CIP Systems, simple validation. 

Good product discharge characteristics with negligible product residues, due to narrow agitator to wall clearances, minimal vessel depth and a special agitator blade design.

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Inerting

Prior to feeding wet cake or slurry into the dryer the vessel interior is inerted by a controlled displacement of the oxygen containing atmosphere with Nitrogen. This procedure prevents the potential formation of an explosive atmosphere in the vessel interior.

Filling

Afbeelding: pharmadry filling

After inertization is completed wet filter cake from a centrifuge or Nutsche filter, or dependent upon the application slurry is fed into the dryer.

Drying

Afbeelding: pharmadry drying

For efficient drying the dryer is typically evacuated in steps and heated up at the same time. During the drying process the product is agitated. The dryer is maintained under vacuum and at the maximum allowable temperature for the product until the final required product humidity level is reached.

Cooling

Afbeelding: pharmadry cooling

After drying is completed the product is cooled down prior to discharging.

Discharging

Afbeelding: pharmadry discharging

The dried and cooled product is discharged thru the side discharge valve. The product is transported to the discharge valve by the agitator.

Cleaning

Afbeelding: pharmadry cleaning

Using spray balls a cleaning fluid is sprayed onto all product wetted internal surfaces for the internal cleaning of the equipment in between individual batches or for product change over. This provides for full and efficient cleaning of the dryer interior.

Technical data

Special properties for the customer’s benefit:

  • calculation, design and manufacture in compliance with Pressure Equipment Directive 97/23/EG or/and ASME U-Stamp as well as with cGMP and FDA guidelines
  • EG type examination certification 03ATEX0246X in accord with PED 94/9/EG or with UL-approved electrical components for operations in class 1, division 1 or 2, group C & D environment
  • double mechanical seal, externally interchangeable, non contacting gas-lubricated (lift-off), dry running contact (contacting sliding surfaces) or liquid-lubricated seal
  • sampler valve
  • pre-piping made of stainless steal on terminal box
  • excellent cleanability using CIP-systems, simple validation


Options:

  • pressure-resistant and sterile versions, isolators (glove box), DQ, IQ, OQ qualification
  • autonomic PLC control or connected to PMSX, heavy current box

Technical data

Dryer
type
 		 Internal
Ø
mm		 Heating area, wetted
m²
 		 Nominal volume
l
 		 Speed
max.
1/min		 Drive
kw
PH 50 450 1.1 50 45 3.0
PH 100 550 1.6 100 35 4.0
PH 200 650 2.1 150 30 5.5
PH 300 800 3.1 260 20 7.5
PH 500 900 4.0 380 14 11.0
PH 750 1060 5.1 580 12 15.0
PH 1000 1200 6.4 850 10 18.5
PH 1500 1350 8.4 1200 9 22
PH 2000 1480 10.0 1590 8 22
PH 2500 1580 11.6 1990 8 30
PH 3000 1700 13.1 2380 7 30
PH 4000 1870 16.1 3190 6 37
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Fields of application
Pharmaceutical
Pharmaceutical
Chemical
Chemical
Fine chemicals
Fine chemicals